No effective specific drug is yet known for the treatment of covid-19 disease caused by the new coronavirus. Some patients are also being tried on trial with some medicines originally intended to treat other diseases.
Supportive treatment is the focus of covid-19, but some medicines are also being tested.
Kristina Nadrah from the UKC Ljubljana Infectious Diseases Clinic explains that supportive treatment comes first. They give patients oxygen and lower their body temperature.
In certain patients with selected indications and at the discretion of the physician team, treatments with medicinal products already known but originally intended for the treatment of other diseases are also being piloted. These include chloroquine and hydroxychloroquine. Chloroquine was used to treat malaria, but now both drugs are used for autoimmune diseases. They are also given lopinavir / ritonavir, originally intended for treatment with hiv virus infection.
Nadrahova explains that they are currently prescribed to patients in combination, but these are trial treatments that they do not know are effective, and they are also very limited by contraindications. They are decided on a case-by-case basis, depending on whether he or she already has certain medicines. a condition in which he cannot receive these medicines.
For lopinavir / ritonavir, however, a recent study has shown that it does not help for those who have been ill for a very long time. However, they do not know how it is for those who are ill for a day or two, so they are still being given it.
The first patient already got it
They have already used the trial drug remdesivir at an infection clinic, which has not yet been registered. There are no clinical studies on the treatment of this medicine. The first patient already got it. According to Nadrahova, it is better, but it is difficult to say whether the disease would be otherwise due to the good treatment support. The following patients in the intensive care unit will also be able to receive the medication if indicated, she explained.
Television Slovenia reported on Monday's Odmeje that remdesivir, which was developed as an anti-Ebola drug, was donated by the US manufacturer to Slovenia, since it cannot be purchased freely because it does not yet have a marketing authorization as an anti-covid-19 drug and is still at the research stage.
According to Nadrahova, treatment at an infection clinic is comparable to treatment across Europe, all medicines are available, our experts are in daily contact with our foreign colleagues. They also agree that they might import some Asian medicine, which is not registered with us. There are many candidate drugs, but very few are known which are actually effective, so time will tell, she said in a video released by the University Clinical Center (UKC) Ljubljana.